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M.Naruszewicz(red.),Ryzykorezydualnechoróbukładusercowo-naczyniowego,Tom2,
Warszawa2010,ISBN978-83-62510-08-5,©MedicalEducationSp.zo.o.
regionalanalyses.REALISTisthefirstmacrovascularsurveytryingtoestablishalink
betweenTG/HDLandriskofcardiovasculareventsonsuchascaleandisthefirst
surveytryingtoestablishalinkbetweenTG/HDLandriskofmicrovascularcompli-
cationsofT2D.REALISTisconductedbyanacademicorganization,theR3iFounda-
tion,throughtheHarvardMedicalSchool.
Therapeuticinterventionaimedatachievementofalllipidtargetsisalsooftenre-
quired.AsoutlinedbyProf.NaruszewiczandhisColleagues,combinationlipid-mo-
difyingtherapywiththeadditionofniacin,afibrateoromega3fattyacidtostatin
therapyincreasestheprobabilityofachievingalllipidgoals.Outcomesstudiesarein
progresstoevaluatewhetherthiscombinationtreatmentstrategiestranslateinaclini-
calbenefitgreaterthanthatachievedwithstatinalone.TheR3ihighlightstheneedto
addresswithlifestyleand/orpharmacotherapythehighlevelofresidualriskofCVD
eventsandmicrovascularcomplicationsamongpatientswithdyslipidemiareceiving
therapyforhighlevelsofLDL-cholesterolandfordiabetesinaccordancewithcurrent
standardsofcare.
ProfessorJean-CharlesFruchart,
PresidentofR3i
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