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M.Naruszewicz(red.),Ryzykorezydualnechoróbukładusercowo-naczyniowego,Tom1,
Warszawa2010,ISBN978-83-930363-0-1,©MedicalEducationSp.zo.o.
PREFACE
D
espiteachievingtargetsforLDLcholesterol,bloodpressureandglycemiain
accordancewithcurrentstandardsofcare,patientswithatherogenicdyslipidemia
remainathighresidualriskofvascularevents.Prof.NaruszewiczandhisColleagues
havewrittenaveryinterestingandwelldocumentedbookonresidualriskreduction.
Findingnewstrategiestoaddressresidualriskisparamount.
InR3i(ResidualRiskReductionInitiative),wearestudyingresidualriskofvascular
eventspersistinginpatientsattreatmentgoalsaccordingtocurrentstandardsofcare
orfailingtomeetgoalsincludingriskrelatedtodyslipidemia,highbloodpressure,hy-
perglycemia,systemicinflammationandunhealthylifestyles.Lifestylemodification
withnutritionandexerciseisanimportanteffectiveandunderutilizedfirststepin
reducingresidualvascularrisk.
Atherogenicdyslipidemiacharacterizedbyelevatedtriglyceridesandlowlevelsof
HDL-cholestroliscommoninpatientswithestablishedcardiovasculardisease,type2
diabetesmellitusormetabolicsyndromeandcontributestobothmacrovascularand
microvascularresidualrisk.However,atherogenicdyslipidemiaislargelyunder-diag-
nosedandunder-treatedinclinicalpractice.WehaverecentlylaunchedinR3ian
epidemiologicalsurvey(REALIST)toassesstherelativeriskofdevelopingacoronary
eventcausedbydyslipidemiaandamicrovascularcomplicationcausedbydyslipide-
miaintype2diabetespatientsatgoalforLDL-cholesteroltreatedornotwithstatin
therapy.REALISTinvolvesalargenumberofcountriesacrosstheworld,allowingfor
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